Similarly, more recent reports showed higher rates of organ-confined disease compared to earlier series (44–73% vs. The authors revealed improved pathological outcomes showing for example decreased rates of positive surgical margins (PSM) ranging from 43–70% in earlier to 0–36% in more recent reports. Their review included publications on SRP between 19 and analyzed the trend over time for complications, pathological, oncological and functional results. demonstrated safety and improvement of different outcomes after SRP ( 4). In this context, the role of salvage radical prostatectomy (SRP) has evolved over the last decade. In consequence, more tailored options that balance the relation of cancer control while optimizing QoL and reducing lasting side effects are needed. However, in the setting of local recurrence, standard management with ADT might result in overtreatment without curative intent that causes several life-lasting side effects and harms Quality of life (QoL) ( 3). While RT is considered a valid second line option after surgical failure, the majority of radiation-recurrent patients will receive androgen deprivation therapy (ADT) ( 1, 2). Yet, 22%–63% of RT patients will develop biochemical recurrence (BCR) after primary treatment ( 1, 2). Next to radical prostatectomy (RP), definitive radiotherapy (RT) represents one of the most common treatment modalities for localized prostate cancer (PCa). Use of Scaffolding Tissue Biografts To Bolster Vesicourethral Anastomosis During Salvage Robot-assisted Prostatectomy Reduces Leak Rates and Catheter Times. Xiongbing Zu, MD, PhD (Department of Urology, Xiangya Hospital, Central South University, Changsha, China).Ĭomment on: Ogaya-Pinies G, Kadakia Y, Palayapalayam-Ganapathi H, et al. Email: This is a Guest Editorial commissioned by Editorial Board Member Dr. Martini-Klinik Prostate Cancer Center, University Hospital Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.
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Given that students are among the most passionate and engaged music fans, to give millions of students the opportunity to get Spotify Premium for half price is indeed the biggest and best student offer in the marketplace. Without the ads now, you also get to study from noon till dawn without interruption. (Do remember to take breaks in between though)įurthermore, you get to have $5 every month. Listen to Villagers of Ioannina City on Spotify. If you can’t live without music (just like me), you’ll thank Spotify for this new plan for students. With their existing premium plan at $9.99 for regular users every month, Spotify is now offering Spotify Premium for Students at a discounted rate of $4.99/month.īasically, you’ll get unlimited high-quality streaming while listening to the songs anywhere without burning through your data. eligible students can get a free month of Spotify Premium, followed by a discounted monthly subscription of just 4.99 per month. What’s the best way? Through music of course! Even Spotify understands the importance of rewinding at the end of a long day. Check the price history of the game to determine how good the deal is in relation to historical low offers. All offers already include discounts from vouchers to save you time and money. GG.deals aggregates game keys from over 40 digital distribution stores so you can find the best deals on video games. Scale the sides of buildings, cars, and walls to ambush enemies from above or make a quick escape.Creep through ruined streets and creole mansions to scavenge for supplies and secrets.Knock walker heads clear off and rip out weapons impaled in their skulls.Cut down both the dead and the living with an arsenal of melee, ranged and makeshift weapons, all physics-based objects you can realistically wield.Will you be able to survive while caught in the middle of this conflict? Can you unravel the mystery that is behind it all? The fate of the city and its survivors rests in your hands. A Vast World To Explore in VRCrafting, exploration, freedom of choice and visceral combat make this a deep, 15+ hour game built for VR. As bodies pile up between warring factions, whispers spread of a long-lost mystery in the city that could turn the tide of the war. The living are not just fighting the dead, but also inflicting pain and brutality upon each other. See how your choices affect the people of New Orleans, and learn to live with the consequences.Ī New, Brutal StoryNew Orleans is at war.Risk life and limb to protect those in need or brutally murder anyone who stands in your way.Take on missions from different factions and survivors to earn valuable resources.Face the undead guns blazing or learn all the ways to sneak and hide among them.With the living, dead, disease and famine as constant threats, you have countless ways to tackle these dangers. Live The Walking Dead's dark drama in your own skin. Survive YOUR WayA new way to live survival horror. Fight the undead, scavenge through the flooded ruins of New Orleans, and face gut-wrenching choices for you and the other survivors. Every challenge you face and decision you make is driven by YOU. LIVE The Walking DeadSaints & Sinners is a game unlike any other in The Walking Dead universe. Interact with UI menus throughout the game using touch input including map zoom. Motion Controls & Touch Menus - Use motion controls for aiming, with a full range of settings to customize to your preference. Play with Your Favorite People -Party with up to three friends and goof around in Giddy Park or dive online into some 8v8 multiplayer in Turf Takeover, vanquishing opponents across a gigantic suburban skirmish. Customize Every Character for Battle - Earn in-game coins only through play, and spend them at the Rux store to unlock cool customization items, characters and perks. Venture to the Outer Edges of Neighborville Offline - Discover Giddy Park, PvE free-roam regions and Private Play modes all without an internet connection. Take your system anywhere, and prepare to kick some grass offline and online in a plant-on-zombie conflict that will take you to the outer edges of Neighborville and back again! Party with up to three friends and goof around in Giddy Park or dive into some 8v8 multiplayer in Turf Takeover, vanquishing opponents, blasting gnome bombs, bouncing on pink ooze – it’s the most fun you’ll have since sliced bread. Now on Nintendo Switch™, tackle hilarious missions and defeat epic bosses in the Weirding Woods, Mount Steep, and Neighborville Town Center to collect medals and unlock outrageous outfits. This thrilling adventure-based on existing records of Bernard Cornwell's ancestors-depicts a time when law and order were ripped violently apart by a pagan assault on Christian England, an assault that came very close to destroying England. Above all, though, he wishes to recover his father's land, the enchanting fort of Bebbanburg by the wild northern sea. ©2005 Bernard Cornwell (P)2014 HarperCollins Publishers. By now he is a young man, in love, trained to fight and ready to take his place in the dreaded shield wall. This is the exciting - yet little known - story of the making of England in the ninth and 10th centuries, the years in which King Alfred, his son and grandson defeated the Danish Vikings who had invaded and occupied three of Englands four kingdoms. The time is around 800 AD when England was but a dream of King Alfred of. This is the thrilling but little-known account of King Alfred, his son, and grandson defeating the Danish Vikings who had invaded and occupied three of England’s four kingdoms during the ninth and tenth centuries. He certainly has no love for Alfred, whom he considers a pious weakling and no match for Viking savagery, yet when Alfred unexpectedly defeats the Danes and the Danes themselves turn on Uhtred, he is finally forced to choose sides. Ive read all the novels by Bernard Cornwell on which these five series are based. Download The Last Kingdom by Bernard Cornwell Pdf book free online. The story is seen through the eyes of Uhtred, a dispossessed nobleman, who is captured as a child by the Danes and then raised by them so that, by the time the Northmen begin their assault on Wessex (Alfred's kingdom and the last territory in English hands) Uhtred almost thinks of himself as a Dane. This is the exciting-yet little known-story of the making of England in the 9th and 10th centuries, the years in which King Alfred the Great, his son and grandson defeated the Danish Vikings who had invaded and occupied three of England's four kingdoms. The first installment of Bernard Cornwell's New York Times bestselling series chronicling the epic saga of the making of England, "like Game of Thrones, but real" (The Observer, London)-the basis for The Last Kingdom, the hit Netflix series. You should also install some extracting tool like Winrar in your computer because highly compressed game setup is provided in a single download link game and it may contains Zip, RAR or ISO file.
Fortunately, any worries about laborious driving to reach missions are laid to rest with shift. With a city the size of San Francisco, the gameworld is huge, and there are hundreds of miles of road for you to drive on and explore. You can highlight any car you like, and with another button press, you're in the driver's seat, ready to take on the criminal horde. Activating shift lets you float above the city, from varying levels of zoom that allow for up-close views of roads all the way to a bird's-eye view. Shifting allows you to take control of any vehicle with just a few buttons presses. While the narrative is completely implausible and at times downright confusing, it allows Driver to free itself from the shackles of the real world and introduce the unique shift mechanic that underpins the entire game. It's in Tanner's coma-induced dreams that Driver takes place the battle against his coma manifests itself as the hunt for Jericho and real-life news reports on the TV in his hospital room influence his actions. Tanner gives chase and-after an explosion-filled action scene of Michael Bay proportions-catches up with the criminal, only to be run down and left in a coma. However, a routine prison transfer gives him the opportunity to escape. After escaping from Istanbul, Jericho takes refuge in San Francisco, only to be tracked down and imprisoned. Now Playing: Driver: San Francisco Video Reviewĭriver: San Francisco picks up where Driv3r left off it continues the story of Tanner and criminal mastermind Jericho. By clicking 'enter', you agree to GameSpot's Team up with your friends to survive, fight to kill the dragonīattle with players, the last survivor winsĭress to impress with unique costume combinationsĮmail: statement of using phone permissions= Multiple Dungeons, Cooperate with your Friends. Over 70 skills and exclusive character emblems for the most skilful 3DMMORPG builderĬombo fighting sequences test your skill and reactionĭynamic lenses create unprecedented 3D fighting feel. Warrior, Archer, Sorceress, Cleric, Academic, Assassin Re-live your favourite game moments as the fate of Lagendia is once again in your hands. Indulge yourself in this classic game, remastered for your mobile. But don’t worry, we’re here to guide you through the process. (See instructions if you don't know how to install: Instructions on how to install)ĥ. How to download Dragon Age 2 on Mac To download Dragon Age 2 on your Mac and dive in the immersive world of the game, you have the option to install Windows on your machine. Request a game or request re-upload, visit Game Request Go deeper into the world of Dragon Age with an entirely new cinematic experience that grabs hold of you from the beginning and never lets goĪll links are interchangeable, you can download different parts on different hosts.Think like a general and fight like a Spartan with dynamic new combat mechanics that put you right in the heart of battle whether you are a mage, rogue, or warrior.Determine your rise to power from a destitute refugee to the revered champion of the land. Embark upon an all-new adventure that takes place across an entire decade and shapes itself around every decision you make.Enjoy the game’s atypical, story-within-a-story nonlinear narrative style Download for Windows Softonic review A full version program for Windows, by BioWare.Dragon Age II is the sequel to Dragon Age: Origins.Īdditional game features include: the ability to choose your character’s class and sex, a new cinematic in-game experience, a nonlinear narrative and the ability to import saved information from earlier Dragon Age games. Dragon Age II Free Download PC Game Cracked in Direct Link and Torrent. It has a gameplay that is perfectly suited for short and quick games. size 36x117 version 1. It's no surprise that it began one of the most important video game sagas for smartphones. 2 days ago &0183 &32 A quaint little Angry Birds themed WoolBattle map. The scoring is based on a three-star system that keeps you wanting to play the same levels until you get all three stars.Īngry Birds Classic is a simple game, and it is fun and has lots of charm. The classic red one doesn't have anything special, but the blackbird will explode, the green bird can come back like a boomerang, among many others.Īngry Birds Classic offers hundreds of different levels in which you have to use your brain and skills. Although Angry Birds 2 can be downloaded for free, there are optional in-app purchases available. Angry Birds 2 is completely free to play. Angry Birds 2 is completely free to play, but there are optional in-app purchases available. In Angry Birds Classic, you have different types of birds to throw. FREE to download - When playing this game, Rovio will offset the carbon footprint caused by the device’s energy consumption. Here are some notes: Please read our MOD Info and installation instructions carefully for the game & app. FREE to download - Angry Birds 2 is completely free to play. Although Angry Birds 2 can be downloaded for free, there are optional in-app purchases available.-When playing this game, Rovio will offset the carbon footprint caused by the device’s energy consumption. With some help from gravity, it will fall down on the structure and take down some of the enemy pigs. You are now ready to download Angry Birds 2 for free. FREE to download - Angry Birds 2 is completely free to play. (Yes, it did exist before Angry Birds Classic.) You'll have to aim well, calculating the strength of the shot and then releasing the bird. In fact, the gameplay is reminiscent of an older genre in which you had to break down castles with stones. You can throw the birds as if you were using a catapult. The objective is to take down all the pigs and cause as much destruction as possible in the process. Angry Birds Classic is a game that challenges you to throw different birds against forts and structures made by little pigs. |